Frosinone have split up the Ciofani brothers, selling defender Matteo to Pescara.
Matteo and Daniel Ciofani were key figures in the side over the last five years, helping them to their first ever promotion into Serie A.
The Canarini won the controversial play-offs with Palermo to make it back into the top flight this summer.
Matteo, the younger of the two brothers at 30 who plays as a right-back, has been sold to Serie B outfit Pescara.
Daniel, a centre-forward aged 33, should remain after contributing 13 goals and five assists in 31 Serie B games last season.