French referee Clement Turpin will officiate Inter’s Champions League opener against Tottenham Hotspur on Tuesday.
It kicks off at San Siro on Tuesday at 17.55 UK time (16.55 GMT).
They are in the same group as Barcelona and PSV Eindhoven.
Turpin is aided by assistant referees Nicolas Danos and Cyril Gringore, additional assistant referees Ruddy Buquet and Nicolas Rainville, plus fourth official Guillaume Debart.
The 36-year-old has a good record with Italian sides, overseeing seven wins, two draws and three defeats.
He officiated Inter only once before, in their 2-0 Europa League qualifier home defeat to Hajduk Split in August 2012.
Turpin oversaw 11 English victories, four draws and only one loss, for Leicester City in the Champions League at Sevilla last season.
He was in charge when Spurs won 2-1 away to Borussia Dortmund in the Champions League in November 2017.