It’s Mauro Icardi, Ivan Perisic and Radja Nainggolan against Harry Kane, Heung-Min Son and Christian Eriksen as Inter welcome Tottenham.
It kicks off at San Siro at 17.55 UK time (16.55 GMT).
It’s Mauro Icardi, Ivan Perisic and Radja Nainggolan against Harry Kane, Heung-Min Son and Christian Eriksen as Inter welcome Tottenham.
It kicks off at San Siro at 17.55 UK time (16.55 GMT).
The Nerazzurri won the Treble with Jose Mourinho in 2010, yet this is their first participation in the group phase of the Champions League since 2011.
They are in a very tough group alongside Barcelona and PSV Eindhoven, while Tottenham are not to be underestimated, as last season they topped their group ahead of Real Madrid and Borussia Dortmund, going out in the Round of 16 to Juventus despite a 2-2 draw in Turin.
Luciano Spalletti’s side aren’t exactly in good form at the moment with four points from four Serie A rounds, including a shock 1-0 home defeat to Parma at the weekend.
Lautaro Martinez and Sime Vrsaljko are injured, with Danilo D’Ambrosio also struggling.
UEFA have this as a 4-2-3-1, but realistically it'll be three at the back with Kwadwo Asamoah as an advanced left-wing-back and Matteo Politano on the right.
As Dalbert, Roberto Gagliardini and Joao Mario are not on the UEFA list due to Financial Fair Play limitations, there is a real shortage of full-backs.
Joao Miranda returns for the first time since his costly error in the defeat to Sassuolo in August.
Nainggolan and Perisic support centre-forward Icardi, who has also suffered from muscular issues over the last couple of weeks.
It’s incredible to think this will be the Champions League career debut for both goalkeeper Samir Handanovic and hitman Icardi, who has 110 goals in 193 Serie A games.
Tottenham seemingly started strong in the Premier League, crushing Manchester United 3-0, but that was followed by back-to-back defeats with Watford and Liverpool.
Spurs surprised everyone by not signing any new players this summer and they might regret that, as Dele Alli, Hugo Lloris and Moussa Sissoko are all out injured.
Curiously, Kieran Trippier and Toby Alderweireld were left behind in London due to a ‘technical decision’ after recent mistakes.
Their greatest strengths are in attack, where Eriksen and ex-Roma man Erik Lamela support South Korean sensation Son and Golden Boot winner Kane.
The most infamous meeting between these sides was a thriller at San Siro in 2010, when Inter were 4-0 up at half-time only for Gareth Bale to run riot with a hat-trick for the final 4-3 result.
Spurs then won the return fixture 3-1 at White Hart Lane.
Inter: Handanovic; Skriniar, De Vrij, Miranda, Asamoah; Brozovic, Vecino; Politano, Nainggolan, Perisic; Icardi
Inter bench: Padelli, Berni, Ranocchia, D'Ambrosio, Borja Valero, Keita, Candreva
Tottenham: Vorm; Aurier, Sanchez, Vertonghen, Davies; Dembele, Dier, Eriksen; Lamela; Son, Kane
Tottenham: Gazzaniga, Rose, Wiks, Wanyama, Walker-Peters, Llorente, Lucas Moura
Ref: Turpin (FRA)