Alessio Romagnoli has reportedly failed a fitness test, so Cristian Zapata will start with Mateo Musacchio as Milan host Chievo.
It kicks off at 14.00 UK time (13.00 GMT), follow the build-up and action from all today’s Serie A games on the LIVEBLOG.
Romagnoli picked up an injury during the final training session and was in doubt for this match.
According to Sky Sport Italia, this morning’s fitness test did not go well and the centre-back has been ruled out of the starting XI.
With Mattia Caldara, Ivan Strinic and Andrea Conti also injured, it means Cristian Zapata has to partner Musacchio in central defence.
Colombia international Zapata had his first appearance of the season in Thursday’s 3-1 Europa League victory over Olympiacos.