Join us for all the build-up and action as it happens from the Europa League games, as Lazio host Olympique Marseille and Milan visit Real Betis.
We begin at the Stadio Olimpico in Rome at 17.55 GMT, when Lazio can practically lock down a place in the Round of 32 with a victory over Marseille.
They already won 3-1 at the Stade Velodrome and Marseille are struggling badly, as last season’s Europa League Finalists have lost three on the bounce in all competition.
It’s a form of Derby della Capitale for ex-Roma men Kevin Strootman and Rudi Garcia, but the Marseille fans are banned from attending due to repeated instances of crowd trouble.
Lazio are only two goals away from becoming the fourth club to score 100 in the Europa League, group stage to Final, after Villarreal, FC Salzburg and Athletic Bilbao
At 20.00 GMT, Milan face a very tricky trip to Real Betis in Seville, having lost the home fixture 2-1.
Gonzalo Higuain, Lucas Biglia, Jack Bonaventura and Mattia Caldara are among those out injured, so Patrick Cutrone must carry the weight of the Rossoneri attack.
Although they are still in second place, another setback would create a risky situation, with Olympiacos not far behind.
Watch Serie A live in the UK on Premier Sports for just £11.99 per month including live LaLiga, Eredivisie, Scottish Cup Football and more. Visit: https://subscribe.premiersports.tv/