Italy give Stefano Sensi his Italy debut with Domenico Berardi, Kevin Lasagna, Francesco Acerbi and Emerson against the USA.
The international friendly kicks off in the Belgian town of Genk at 19.45 GMT.
You can follow the build-up and action as it happens while giving your views on the LIVEBLOG.
Italy give Stefano Sensi his Italy debut with Domenico Berardi, Kevin Lasagna, Francesco Acerbi and Emerson against the USA.
The international friendly kicks off in the Belgian town of Genk at 19.45 GMT.
You can follow the build-up and action as it happens while giving your views on the LIVEBLOG.
Roberto Mancini’s men are out of the Nations League after a 1-0 win in Poland and 0-0 draw with Portugal, highlighting the difficulty in scoring goals despite dominating both games with some sparkling approach play.
Several star names have been sent home ahead of this friendly, so Lorenzo Insigne, Ciro Immobile, Alessandro Florenzi, Lorenzo Pellegrini, Jorginho and Giorgio Chiellini are unavailable.
Instead, Mancini gives Sassuolo midfielder and former Italy Under-21 international Sensi his senior debut in midfield.
Many expect Brescia teenage talent Sandro Tonali to come off the bench for his bow, while Juventus striker Moise Kean is also in the squad.
Sensi has the chance to play alongside Sassuolo teammate Berardi, who completes the trident attack with Udinese forward Lasagna and Fiorentina’s Federico Chiesa.
Lasagna has made two Italy appearances, both as a substitute for just 25 minutes of football, but he did provide the assist for Cristiano Biraghi’s winner in Poland.
Lazio centre-back Francesco Acerbi has gone from strength to strength since leaving Sassuolo, while Emerson Palmieri is finding his feet again at Chelsea after a long injury lay-off.
There are some familiar names in the USA squad, as the sons of ex-Inter striker Jurgen Klinsmann and former Milan hero George Weah have chosen to represent America at international level.
Christian Pulisic is the big star name, as the 20-year-old Borussia Dortmund midfielder is reportedly on the verge of a January transfer to Chelsea.
DeAndre Yedlin has impressed at Newcastle United in the Premier League, with strikers Bobby Wood and Josh Sargent shining in the Bundesliga.
The starting XI has an average age of 22 years and 71 days, making it the youngest USA XI in the modern era, and they approach this in a 3-5-2 formation
As this is a friendly, VAR technology will be used.
Italy: Sirigu; De Sciglio, Bonucci, Acerbi, Emerson; Barella, Sensi, Verratti; Chiesa, Lasagna, Berardi
Italy bench: Cragno, Donnarumma, Mancini, Biraghi, Gagliardini, Pavoletti, Grifo, Rugani, Tonali, Kean, Politano
USA: Horvath; Carter-Vickers, Zimmerman, Long; Cannon, Delgado, Adams, Acosta, Moore; Pulisic, Sargent
USA bench: Guzan, Miazga, Wood, Weah, Lletget, Green, Villafana, Trapp, Gall
Ref: Cakir (TUR)