Lazio have already qualified for the Last 32 of the Europa League, so Simone Inzaghi rests his stars for the trip to Apollon Limassol.
The Biancocelesti are second in the table behind Eintracht Frankfurt, but are already guaranteed to progress.
As a result, the Coach has left the likes of Tomas Strakosha, Luis Alberto and Sergej Milinkovic-Savic at home.
Top-scorer Ciro Immobile is also rested, while Lucas Leiva won’t make the trip to Cyprus.
Lazio squad to face Apollon Limassol: Alia, Proto, Guerrieri, Acerbi, Armini, Bastos, Caceres, Durmisi, Luiz Felipe, Wallace, Berisha, Cataldi, Lulic, Murgia, Rezzi, Caicedo, Correa, Rossi