Roma send Umar Sadiq to Perugia after his Glasgow Rangers spell was cut short, while Panagiotis Tachtsidis joins Serie B side Lecce.
Striker Sadiq struggled to settle in Scotland and the 21-year-old Nigerian managed just 161 minutes of football over five competitive games this season.
He was returned to Roma, who immediately sent him out on loan to Serie B outfit Perugia.
Also going to Serie B is Greek international Tachtsidis, a former Roma and Torino midfielder who had most recently been playing for Nottingham Forest.
He has signed for Lecce, on loan with option to buy that becomes mandatory if the team earns promotion to Serie A.