Milan are expected to give Lucas Paquetá his debut from the start in the Coppa Italia Round of 16 against Sampdoria today.
The one-off match is at Marassi at 17.00 GMT.
Suso, Lucas Biglia, Jack Bonaventura, Andrea Bertolacci, Mattia Caldara and Ivan Strinic are still out injured.
It’s reported Rossoneri Coach Gennaro Gattuso will gamble with his new Brazilian signing from the start.
The 21-year-old arrived from Flamengo during the January transfer window, becoming the most expensive ever signing from Brazil to Italy.
Gattuso looks to maintain his 4-3-3 formation with Paquetá in midfield alongside Tiemoue Bakayoko and Franck Kessie.
Gonzalo Higuain is guaranteed a starting spot with Samu Castillejo and Hakan Calhanoglu likely flanking the Chelsea transfer target.
The only real doubt is between Mateo Musacchio and Cristian Zapata at centre-back.
As for Sampdoria, they should use Gaston Ramirez in the trequartista role behind Gianluca Caprari and on form veteran Fabio Quagliarella, leaving ex-Milan man Riccardo Saponara on the bench.
Manolo Gabbiadini has only just arrived from Southampton and is not expected to take part, while Edgar Barreto and Bartosz Bereszynski are injured.
The winners go on to face Napoli or Sassuolo in the Quarter-Final.
Sampdoria: Rafael; Sala, Andersen, Tonelli, Murru; Praet, Ekdal, Linetty; Ramirez; Quagliarella, Caprari
Milan: Reina; Abate, Musacchio, Romagnoli, Rodriguez; Kessie, Bakayoko, Paquetá; Castillejo, Higuain, Calhanoglu