Ciro Immobile is not in Lazio’s XI for their Serie A match against Empoli this evening, but Romulo makes his debut.
Immobile joins Luis Alberto out of Lazio’s squad after they failed to prove their fitness in time for the game.
However, Romulo is selected for the first time since his deadline-day arrival from Genoa last month, playing as a right wingback.
Empoli, meanwhile, hand debuts to new signings Cristian Dell’Orco and Diego Farias.
The Tuscans have avoided defeat in six of their last 16 League meetings with Lazio, but they have gone seven matches without a win, while the Aquile have come out on top in the last four encounters.
Another victory for Simone Inzaghi’s side would send them into the Champions League places, albeit with a game in hand.
Lazio: Strakosha; Bastos, Acerbi, Radu; Romulo, Milinkovic, Lucas, Berisha, Lulic; Correa, Caicedo
Subs: Proto, Guerrieri, Luiz Felipe, Kalaj, Zitelli, Patric, Badelj, Marusic, Cataldi, Jordao, Durmisi, Neto
Empoli: Provedel; Veseli, Silvestre, Dell’Orco; Di Lorenzo, Krunic, Bennacer, Traore, Pasqual; Farias, Caputo
Subs: Perucchini, Antonelli, Rasmussen, Diks, Maietta, Nikolaou, Pajac, Acquah, Brighi, Salih, Mchedlidze, Oberlin