Jose Callejon left last season’s defeat to Fiorentina in the past and assured Napoli “believe in the Scudetto” after closing the gap to nine points.
It kicks off at 17.00 GMT, click here for the line-ups and LIVEBLOG.
When the Partenopei were beaten here 3-0 in April by a Giovanni Simeone hat-trick, with Kalidou Koulibaly sent off, it practically handed the Serie A title to Juventus.
“Last season we didn’t approach the game well or play the way we wanted to, but that’s in the past and it no longer matters.
“We are here now, hope to put in a good performance and win the match,” the Spaniard told Sky Sport Italia.
“Fiorentina are in good shape, feeling confident and have talented players. It’s going to be difficult, but we are here to win the game and stay in the top places.
“We believe in the Scudetto, that’s why we are here and keep going, then we’ll see what happens.”
Watch Serie A live in the UK on Premier Sports and get your first month free, visit https://www.premiersports.com/football/eleven-sports-customer.html