Juventus have Andrea Barzagli back in the squad to face Sassuolo, but Leonardo Bonucci and Giorgio Chiellini are still out.
It kicks off on Sunday at 17.00 GMT, click here for a match preview.
Barzagli returns to the fold after several months on the treatment table, but Chiellini, Bonucci, Juan Cuadrado and Douglas Costa are unavailable.
The 37-year-old defender has not featured in a Bianconeri jersey since his seven minutes on the field in a 2-1 home defeat to Manchester United on November 7.
Juventus squad for Sassuolo: Szczesny, De Sciglio, Caceres, Pjanic, Khedira, Ronaldo, Dybala, Alex Sandro, Matuidi, Barzagli, Mandzukic, Kean, Cancelo, Pinsoglio, Perin, Emre Can, Rugani, Bentancur, Bernardeschi, Spinazzola