Cagliari Coach Rolando Maran maintains the trip to Bologna will be a relegation dogfight, “but not a decisive result” for their prospects.
It kicks off at the Stadio Dall’Ara at 11.30 GMT, click here for a match preview.
The Sardinians beat Inter last week to break nine points clear of Bologna in the relegation zone, so a positive outcome here could put them comfortably mid-table.
“It’s an important match, it is a head-to-head, but won’t be a decisive result,” said Maran in his Press conference.
“Bologna didn’t get the results they deserved this season. They’ve found more confidence and form under Sinisa Mihajlovic, so we need to be on full alert. They’ve changed so much with new players and Coach, they’re practically a different team.
“I hope our mentality won’t be any different from last week. We’ve got to focus only on ourselves and realise our chances were created against Inter because we played without anxiety.
“It’s been too long since we came back from an away fixture feeling happy.”
Paolo Faragò and Luca Cigarini are suspended, with Lucas Castro, Alberto Cerri and Ragnar Klavan injured, but creative midfielder Valter Birsa is back in the squad.
Croatia international Filip Bradaric is expected to step in to the midfield breach and Maran noted this is “a great opportunity for him. Like all the players who went all the way in the World Cup, his form this season has been hit and miss.”
Cagliari squad for Bologna: Rafael, Aresti, Cragno; Pellegrini, Cacciatore, Pisacane, Lykogiannis, Ceppitelli, Srna, Leverbe, Romagna; Bradaric, Birsa, Oliva, Barella, Padoin, Ionita, Deiola, Marongiu; Joao Pedro, Pavoletti, Despodov, Thereau