Atalanta dominated the match with numerous chances, including two big Hans Hateboer misses, a goal-line clearance and series of Bartlomiej Dragowski saves, but somehow Empoli earned a point.
The result means the Orobici drop down to sixth place, two points behind Milan in that fourth Champions league spot.
Empoli remain in the bottom three, but only two points adrift of Bologna.
Watch Serie A live in the UK on Premier Sports for just £11.99 per month including live LaLiga, Eredivisie, Scottish Cup Football and more. Visit: https://subscribe.premiersports.tv/