Romelu Lukaku passes a late fitness test to start with Lautaro Martinez, Stefano Sensi and Roberto Gagliardini as Inter host Slavia Prague in their Champions League opener.
It kicks off at San Siro at 17.55 UK time (16.55 GMT), you can follow the build-up and action as it happens from this game and Napoli-Liverpool on the LIVEBLOG.
The Nerazzurri have had the perfect start under Antonio Conte, winning all three Serie A games and sitting alone on top of the table.
Now their Champions League campaign begins too against Czech Republic title holders Slavia Prague, in a very tough group that also includes Barcelona and Borussia Dortmund.
Lukaku was purchased from Manchester United for €65m plus bonuses and scored in his first two Serie A games, but fired blanks and looked shaky in the 1-0 victory over 10-man Udinese on Saturday evening.
That is largely because he had a back problem in the warm-up and remained a doubt to the last minute tonight, but has been given the all-clear to start with Argentina international Lautaro Martinez.
Alexis Sanchez is on the bench and ready to come on for extra fire-power, along with Matteo Politano.
Valentino Lazaro was expected to get his debut on the right flank, with Cristiano Biraghi also pushing Kwadwo Asamoah for a spot on the left.
However, Antonio Candreva and Asamoah retain their places, as the only real change is Gagliardini in for Matias Vecino alongside Sensi.
Diego Godin is rested ahead of this weekend’s Derby della Madonnina with Milan.
Slavia Prague drop centre-forward Milan Skoda, preferring a 4-4-2 formation with more mobile strikers Peter Olayinka and Josef Husbauer.
Nicolae Stanciu is a familiar face for Inter fans, as he already scored against them for Vaslui in the Europa League play-offs in 2012-13.
Ladislav Takacs has not even made it to the bench after an injury.
The referee is Ruddy Buquet with fellow Frenchman Francois Letexier in the VAR booth.
Inter: Handanovic; D'Ambrosio, De Vrij, Skriniar; Candreva, Gagliardini, Brozovic, Sensi, Asamoah; R Lukaku, Lautaro Martinez
Inter bench: Padelli, Godin, Alexis Sanchez, Vecino, Politano, Lazaro, Barella
Slavia Prague: Kolar; Coufal, Kudela, Hovorka, Boril; Soucek, Husbauer, Traore, Stanciu; Masopust, Olayinka
Slavia bench: Markovic, Tecl, Zeleny, Provod, Skoda, Frydych, Yusuf Helal
Ref: Buquet (FRA)
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