Roma start Henrikh Mkhitaryan with Edin Dzeko and Justin Kluivert, as Bologna hope Riccardo Orsolini and Mattia Destro can give them a ninth consecutive home win.
It kicks off at the Stadio Dall’Ara at 14.00 UK time (13.00 GMT).
You can follow all the build-up and action as it happens from today’s SIX Serie A games on the LIVEBLOG.
Roma start Henrikh Mkhitaryan with Edin Dzeko and Justin Kluivert, as Bologna hope Riccardo Orsolini and Mattia Destro can give them a ninth consecutive home win.
It kicks off at the Stadio Dall’Ara at 14.00 UK time (13.00 GMT).
You can follow all the build-up and action as it happens from today’s SIX Serie A games on the LIVEBLOG.
The Giallorossi are brimming with confidence under new Coach Paulo Fonseca after a 4-2 victory over Sassuolo and Thursday’s 4-0 Europa League win against Istanbul Basaksehir.
Due to various tweaks of the fixture list, this is Roma’s first game of the season outside the Stadio Olimpico, as the only away match was the derby with Lazio.
Chris Smalling, Cengiz Under, Davide Zappacosta and Diego Perotti are still out injured.
Kluivert gets the nod rather than Nicolò Zaniolo in the supporting trio with Lorenzo Pellegrini and Mkhitaryan behind Dzeko.
Bologna have won their last eight Serie A home games and a victory today would set a new all-time club record.
It’s a remarkable achievement considering the circumstances, as Coach Sinisa Mihajlovic was diagnosed with leukaemia in July and is currently undergoing his second course of chemotherapy.
The squad fought back from 3-1 down to beat Brescia 4-3 last week and on the way home, the team stopped the bus outside his hospital window to sing football chants.
Miha keeps up to date via videolink and even gives half-time team talks from his hospital bed.
Danilo is still out injured, so Mattia Bani is again chosen at centre-back with Stefano Denswil, while veterans Gary Medel and Andrea Poli form the midfield.
Riccardo Orsolini, Roberto Soriano and Nicola Sansone fan out behind Destro, with a style of football not dissimilar to Fonseca’s Roma.
Rodrigo Palacio is left on the bench.
Bologna: Skorupski; Tomiyasu, Bani, Denswil, Dijks; Poli, Medel, Soriano; Orsolini, Destro, Sansone
Roma: Pau Lopez; Florenzi, Mancini, Fazio, Kolarov; Cristante, Veretout; Kluivert, Pellegrini, Mkhitaryan; Dzeko
Ref: Pairetto