Alexis Sanchez gets his first start in the Inter jersey alongside Lautaro Martinez, as they target a sixth win out of six against Sampdoria.
It kicks off at Marassi at 17.00 UK time (16.00 GMT).
Follow all the build-up and action as it happens from this game and Sassuolo–Atalanta on the LIVEBLOG.
Alexis Sanchez gets his first start in the Inter jersey alongside Lautaro Martinez, as they target a sixth win out of six against Sampdoria.
It kicks off at Marassi at 17.00 UK time (16.00 GMT).
Follow all the build-up and action as it happens from this game and Sassuolo-Atalanta on the LIVEBLOG.
Antonio Conte’s men are top of the table after winning all five Serie A games, but have a showdown with Barcelona coming up in the Champions League midweek, so rest Romelu Lukaku, giving Alexis Sanchez his first start since the loan move from Manchester United.
Diego Godin, Danilo D’Ambrosio and Nicolò Barella are also rested, with Alessandro Bastoni and Roberto Gagliardini stepping in.
Eusebio Di Francesco remains under pressure after four defeats out of five, the exception a 1-0 home victory over Torino.
Manolo Gabbiadini scored that goal, but he is ruled out today by injury, while last season’s Capocannoniere Fabio Quagliarella has shaken off a muscular issue to start.
There is a change of system to an apparent 3-4-2-1, as Emiliano Rigoni and Jakub Jankto support Quagliarella.
Gonzalo Maroni is still trying to recover from a sprained ankle he sustained in the Coppa Italia last month.
Sampdoria: Audero; Bereszynski, Chabot, Colley; Depaoli, Linetty, Ekdal, Murru; Rigoni, Jankto; Quagliarella
Sampdoria bench: Raspa, Falcone, Augello, Vieira, Barreto, Bonazzoli, Ramirez, Caprari, Thorsby, Regini, Ferrari, Leris
Inter: Handanovic; Skriniar, De Vrij, Bastoni; Candreva, Gagliardini, Brozovic, Sensi, Asamoah; Alexis Sanchez, Lautaro Martinez
Inter bench: Padelli, Godin, Ranocchia, D’Ambrosio, Vecino, Lazaro, Borja Valero, Dimarco, Barella, Biraghi, R Lukaku, Politano