Atalanta field almost a full-strength XI against Domenico Berardi’s Sassuolo, including Duvan Zapata, Josip Ilicic and Papu Gomez.
It kicks off at 19.45 UK time (18.45 GMT), follow the build-up and action as it happens on the LIVEBLOG.
Sassuolo have a perfect home record this season, but have lost all three of their away games, so are hoping to keep that trend going this evening.
However, home advantage isn’t really an issue in this case, because Atalanta played many times at the Mapei Stadium, using it as their base for the Europa League matches.
Rogerio is out for a couple of months with a knee ligament injury, but the only doubt for Roberto De Zerbi was upfront, where Gregoire Defrel completes the trident attack with Domenico Berardi and Jeremie Boga, unexpectedly dropping hitman Francesco Caputo to the bench.
Atalanta got back on track midweek with a 2-0 victory away to Roma, which saw Duvan Zapata come off the bench to make the difference.
He starts this time with Ilicic and Papu Gomez, but Luis Muriel is still unavailable due to a bout of tonsillitis.
The surprise is in goal, where Marco Sportiello gets a rare chance to start rather than Pierluigi Gollini.
Sassuolo: Consigli; Toljan, Chiriches, Ferrari, Peluso; Duncan, Obiang, Bourabia; Berardi, Defrel, Boga
Atalanta: Sportiello; Toloi, Djimsiti, Masiello; Hateboer, Freuler, Pasalic, Gosens; Gomez, Ilicic, Duvan Zapata
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