Inter will try again to recapture the top spot with Romelu Lukaku and Lautaro Martinez leading the way against Rodrigo Palacio’s Bologna.
It kicks off at the Stadio Dall’Ara at 17.00 GMT.
You can follow all the build-up and action from this game, Roma-Napoli and Torino-Juventus on the LIVEBLOG.
The Nerazzurri can at least temporarily take the leadership with a victory at the Dall’Ara, but fatigue is beginning to set in amid the injury crisis, which continues to rule out Alexis Sanchez, Danilo D’Ambrosio and now also Kwadwo Asamoah.
Stefano Sensi returns, but is only fit for a spot on the bench, so Roberto Gagliardini is again pulling the midfield reins.
Valentino Lazaro has been something of a mystery since arriving over the summer for €22.5m, as he’s had only two substitute appearances in all competition.
In order to rest Antonio Candreva, the 23-year-old Austria international is given his first start in an Inter jersey on the right wing.
There’s no rest for Lukaku and Lautaro Martinez, as they are again the front two, with Matteo Politano and Sebastiano Esposito the only alternatives.
Bologna have struggled lately with only one win in the last six games, as coach Sinisa Mihajlovic’s absence for his third course of chemotherapy is starting to take its toll.
Mattia Destro, Takehiro Tomiyasu and Mitchell Dijks are still injured, but former Inter midfielder Gary Medel is back for a spot on the bench after several weeks out of action.
Another ex-Nerazzurri star takes the centre-forward role, as Palacio is on sparkling form at the age of 37.
He has support from Riccardo Orsolini, Roberto Soriano and Nicola Sansone.
Inter are unbeaten at the Stadio Dall’Ara since February 2002, emerging with 11 Serie A wins and three draws.
Bologna: Skorupski; Mbaye, Danilo, Bani, Krejci; Poli, Svanberg; Orsolini, Soriano, Sansone; Palacio
Bologna bench: Da Costa, Sarr, Denswil, Medel, Paz, Santander, Skov Olsen, Corbo, Juwara, Cangiano, Schouten, Dzemaili
Inter: Handanovic; Skriniar, De Vrij, Bastoni; Lazaro, Gagliardini, Brozovic, Barella, Biraghi; R Lukaku, Lautaro Martinez
Inter bench: Padelli, Berni, Godin, Vecino, Ranocchia, Sensi, Politano, Borja Valero, Dimarco, Esposito, Candreva
Ref: La Penna
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