Juventus look to Daniele Rugani, Aaron Ramsey, Cristiano Ronaldo and Gonzalo Higuain against Lokomotiv Moscow in the Champions League.
It kicks off at the Stadion Lokomotiv at 17.55 GMT.
You can follow all the build-up and action as it happens from this game and Atalanta-Manchester City on the LIVEBLOG.
Juventus look to Daniele Rugani, Aaron Ramsey, Cristiano Ronaldo and Gonzalo Higuain against Lokomotiv Moscow in the Champions League.
It kicks off at the Stadion Lokomotiv at 17.55 GMT.
You can follow all the build-up and action as it happens from this game and Atalanta-Manchester City on the LIVEBLOG.
The Bianconeri will mathematically seal their place in the Round of 16 with a victory in Moscow, so there is plenty of motivation to do well.
It is also far from taken for granted, considering Lokomotiv Moscow were 1-0 up in Turin until a late Dybala brace turned it around for 2-1.
Maurizio Sarri is forced into some changes in Russia, as Juan Cuadrado is suspended and makes way for Danilo, while Matthijs de Ligt sprained his ankle, so Daniele Rugani gets the nod rather than Merih Demiral in only his second appearance of the season, his first in the Champions League.
There are also adjustments upfront, as Ramsey returns in the trequartista role behind the strikers, taking over from Federico Bernardeschi.
Gonzalo Higuain partners Cristiano Ronaldo, as Dybala had a stomach bug yesterday and is not feeling 100 per cent fit.
Lokomotiv Moscow are still without Luka Djordjevic, Anton Miranchuk, Fedor Smolov, Jefferson Farfan and Boris Rotenberg.
Eder is again the only real option to lead the attack, with support from Aleksei Miranchuk and ex-Inter midfielder Joao Mario.
Lokomotiv Moscow: Guilherme; Ignatyev, Höwedes, Corluka, Rybus; Zhemaletdinov, Krychowiak, Barinov, Joao Mario; Al Miranchuk, Eder
Lokomotiv bench: Kochenkov, Zhivoglyadov, Idowu, Kolomeytsev, Murilo, Magkeev, Tugarev
Juventus: Szczesny; Danilo, Bonucci, Rugani, Alex Sandro; Khedira, Pjanic, Rabiot; Ramsey; Higuain, Ronaldo
Juventus bench: Buffon, De Sciglio, Dybala, Douglas Costa, Matuidi, Demiral, Bentancur
Ref: Buquet (FRA)