Sassuolo have been dealt a blow after striker Gregoire Defrel picked up an ankle injury.
Sassuolo’s official website explains Defrel pulled up in training on Wednesday and was later found to have suffered an injury to the capsular ligaments in his left ankle.
The Frenchman only returned to the Neroverdi from Roma over the summer.
Despite commanding a reported €16m, he has managed just one goal in eight appearances so far this season.
Meanwhile, Vlad Chiriches, Gianluca Pegolo and captain Domenico Berardi trained individually, leaving them all doubtful for the visit of Lazio on Sunday.
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