Atalanta can reach the Champions League Round of 16 with a victory away to Shakhtar Donetsk, so rely on Papu Gomez, Luis Muriel and Mario Pasalic.
It kicks off in Donetsk at 17.55 GMT and represents a head-to-head for qualification.
Atalanta can reach the Champions League Round of 16 with a victory away to Shakhtar Donetsk, so rely on Papu Gomez, Luis Muriel and Mario Pasalic.
It kicks off in Donetsk at 17.55 GMT and represents a head-to-head for qualification.
Gian Piero Gasperini’s men could make history, as no side has ever reached the last 16 after losing the first three group games.
In order to achieve this, they need to win in Ukraine and hope Manchester City avoid defeat to Dinamo Zagreb.
There are serious injury problems, because Josip Ilicic has joined Duvan Zapata and Simon Kjaer on the treatment table, while Rafael Toloi is suspended.
There were reports Luis Muriel would again be benched, moving Gomez to a False 9 role, supported by Mario Pasalic and Ruslan Malinovskyi.
However, with the need for a victory, Muriel does start with Gomez and Pasalic, leaving Ukraine international Malinovskyi on the bench.
Shakhtar Donetsk can afford to draw and still go through, as long as Dinamo Zagreb do not beat Manchester City.
They have a full squad to choose from, as Tete, Viktor Kovalenko and Taison fan out behind centre-forward Junior Moraes.
He is the one to watch, as Junior Moraes has scored 16 goals in 22 competitive games this season.
The Ukrainians earned a 2-1 win at San Siro, snatching victory on the counter-attack when under pressure.
Shakhtar Donetsk: Pyatov; Dodo, Kryvtsov, Matviyenko, Ismaily; Stepanenko, Alan Patrick; Tete, Kovalenko, Taison; Junior Moraes
Shakhtar Donetsk bench: Shevchenko, Khocholava, Marcos Antonio, Dentinho, Marlos, Konoplyanka, Solomon
Atalanta: Gollini; Masiello, Djimsiti, Palomino; Castagne, De Roon, Freuler, Gosens; Pasalic, Gomez; Muriel
Atalanta bench: Sportiello, Arana, Malinovskyi, Hateboer, Ibanez, Traore, Barrow
Ref: Zwayer (GER)