Roma look to Nicolò Zaniolo, Stephan El Shaarawy and Edin Dzeko for a tricky trip to a Genoa side who aren’t safe from relegation yet.
It kicks off at Marassi at 17.00 UK time (16.00 GMT).
You can follow the action as it happens from all six Serie A games on the LIVEBLOG.
Roma look to Nicolò Zaniolo, Stephan El Shaarawy and Edin Dzeko for a tricky trip to a Genoa side who aren’t safe from relegation yet.
It kicks off at Marassi at 17.00 UK time (16.00 GMT).
You can follow the action as it happens from all six Serie A games on the LIVEBLOG.
The Giallorossi are not just targeting fourth place, but with Inter slowing down considerably after three consecutive draws, can drag them back into the fight too.
Claudio Ranieri made this trip without injured Daniele De Rossi, Davide Santon and Diego Perotti, but Kostas Manolas and Federico Fazio reunite in central defence.
Zaniolo is returned to the more advanced role in a 4-2-3-1 formation with Lorenzo Pellegrini and El Shaarawy supporting Dzeko.
Genoa are by no means clear of relegation, especially after Empoli beat Fiorentina earlier this afternoon, and are increasingly desperate for a positive result under Cesare Prandelli.
Stefano Sturaro is out for the rest of the season with a knee ligament injury, joined in the stands by Andrea Favilli, Luca Mazzitelli and Oscar Hiljemark.
Gianluca Lapadula again gets the nod in attack with Christian Kouame, leaving Goran Pandev on the bench, while the Grifone continue to work on their 3-5-2 approach.
Genoa: Radu; Biraschi, Romero, Zukanovic; Bessa, Lerager, Radovanovic, Veloso, Criscito; Lapadula, Kouame
Roma: Mirante; Florenzi, Manolas, Fazio, Kolarov; Nzonzi, Cristante; Zaniolo, Pellegrini, El Shaarawy; Dzeko
Ref: Mazzoleni