Roma give Carles Perez his first start with Lorenzo Pellegrini, Diego Perotti and Edin Dzeko in the Europa League Round of 32 with Belgians KAA Gent.
The first leg kicks off at the Stadio Olimpico at 20.00 GMT.
You can follow the build-up and action as it happens from this game and Ludogorets-Inter on the LIVEBLOG.
Roma give Carles Perez his first start with Lorenzo Pellegrini, Diego Perotti and Edin Dzeko in the Europa League Round of 32 with Belgians KAA Gent.
The first leg kicks off at the Stadio Olimpico at 20.00 GMT.
The Giallorossi are going through a rough period in both Serie A and the Coppa Italia lately, losing four of their last five games and drawing the other with arch rivals Lazio.
They are without a victory since the 3-1 away to Genoa on January 19.
Aleksandar Kolarov and Jordan Veretout return, after they were benched for the 2-1 defeat to Atalanta, while January signing Perez is given his first start in a Roma jersey, completing the attacking front with Pellegrini, Perotti and Dzeko.
The injury list still includes Javier Pastore, Amadou Diawara, Nicolò Zaniolo, Antonio Mirante, Davide Zappacosta and Merit Cetin, while Bruno Peres is not on the UEFA list.
Belgian side KAA Gent are without Roman Yaremchuk, while Laurent Depoitre is thrown straight into the starting XI, even though he hasn’t played since January 25.
These sides have met before, in 2009-10 when Roma knocked Gent out of the Europa League preliminary round, winning 3-1 at the Olimpico and 7-1 in Belgium.
Roma: Pau Lopez; Spinazzola, Fazio, Smalling, Kolarov; Veretout, Cristante; Carles Perez, Pellegrini, Perotti; Dzeko
Roma bench: Fuzato, Cengiz Under, Santon, Kalinic, Mancini, Mkhitaryan, Kluivert
KAA Gent: Kaminski; Lustig, Plastun, Ngadeu-Ngadjui, Mohammadi; Kums, Owusu, Odjidja; Bezus; Depoitre, David
Gent bench: Coosemans, Chakvetadze, Niangbo, Kvilitaia, Castro-Montes, Marreh, Godeau
Ref: Kabakov (BUL)