Juventus have Miralem Pjanic back with Paulo Dybala, Cristiano Ronaldo and Juan Cuadrado in the Champions League clash with Lyon, as Bruno Guimaraes starts.
It kicks off at the Groupama Stadium at 20.00 GMT.
You can follow the build-up and action as it happens and give your views on the LIVEBLOG.
This is the first leg in the Champions League Round of 16, with the decider in Turin on March 17.
Juventus have Miralem Pjanic back with Paulo Dybala, Cristiano Ronaldo and Juan Cuadrado in the Champions League clash with Lyon, as Bruno Guimaraes starts.
It kicks off at the Groupama Stadium at 20.00 GMT.
You can follow the build-up and action as it happens and give your views on the LIVEBLOG.
This is the first leg in the Champions League Round of 16, with the decider in Turin on March 17.
Maurizio Sarri is still unbeaten in Europe on the Juventus bench, having qualified from the group stage with two games to spare.
He has a full squad to choose from, save for Merih Demiral, as Pjanic is back from a muscular problem and goes straight into the starting XI with Rodrigo Bentancur and Adrien Rabiot.
The trident is confirmed with Cuadrado joining Dybala and Ronaldo, leaving Gonzalo Higuain on the bench.
Cristiano Ronaldo has 25 goals in 30 competitive games for Juventus this season, but only two in six Champions League fixtures.
Lyon have numerous injury problems that have gone on for some months, missing Rafael, Youssouf Kone, Jeff Reine-Adelaide and above all top scorer Memphis Depay.
The injury crisis has allowed them to discover Houssem Aouar in midfield and he has already been mentioned as a potential transfer target for Juventus.
It had been predicted that Martin Terrier would start, but January signing from Atletico Paranaense Bruno Guimaraes gets the nod instead.
He was picked up for €20m and has made only one Ligue 1 appearance for Lyon so far, the 2-0 victory away to Metz on February 21.
Moussa Dembele has 14 goals this season and is supported by Karl Toko-Ekambi.
Lyon: Lopes; Denayer, Marcelo, Marçal; Dubois, Bruno Guimaraes, Tousart, Aouar, Cornet; Dembele, Toko-Ekambi
Lyon bench: Tatarusanu, Andersen, Terrier, Traore, Mendes, Tete, Caqueret
Juventus: Szczesny; Danilo, Bonucci, De Ligt, Alex Sandro; Bentancur, Pjanic, Rabiot; Cuadrado, Dybala, Cristiano Ronaldo
Juventus bench: Buffon, De Sciglio, Ramsey, Matuidi, Higuain, Rugani, Bernardeschi
Ref: Gil Manzano (ESP)