Pau Lopez performed heroics in the Roma goal, but even he could not keep out Jose Callejon and the Lorenzo Insigne right-foot curler for Napoli.
Henrikh Mkhitaryan scored an impressive temporary equaliser for the Giallorossi, but it was victory for the Partenopei at the Stadio San Paolo.
They did it in style, Callejon sliding on to a Mario Rui cross and Insigne’s trademark finish into the top corner, but Arkadiusz Milik also rattled the woodwork with his header.
Watch Serie A live in the UK on Premier Sports for just £9.99 per month including live LaLiga, Eredivisie, Scottish Cup Football and more. Visit: https://www.premiersports.com/subscribenow