Juventus have an experimental line-up for their trip to Cagliari, starting Gigi Buffon, Simone Muratore, Gonzalo Higuain and Cristiano Ronaldo.
It kicks off at the Sardegna Arena at 20.45 UK time (19.45 GMT).
The Bianconeri have already won their ninth consecutive Serie A title, but Ronaldo is still chasing Ciro Immobile for the Capocannoniere crown.
CR7 will not rest, so he leads the attack with Higuain – whose record Immobile might be about to break – and Federico Bernardeschi.
Adrien Rabiot is suspended, with Paulo Dybala, Douglas Costa, Danilo, Mattia De Sciglio and Sami Khedira injured, so 22-year-old Simone Muratore gets his first Serie A start ahead of a transfer to Atalanta.
Cagliari look as if they’ll change management again this summer, as Walter Zenga failed to make improvements after Rolando Maran was fired.
Nahitan Nandez is suspended, with Radja Nainggolan, Luca Pellegrini, Christian Oliva and Leonardo Pavoletti injured.
Joao Pedro partners Giovanni Simeone, with 20-year-old Luca Gagliano given his debut.
Cagliari: Cragno; Walukiewicz, Ceppitelli, Klavan; Faragò, Rog, Ionita, Mattiello; Joao Pedro, Simeone, Gagliano
Juventus: Buffon; Cuadrado, Bonucci, Rugani, Alex Sandro; Bentancur, Pjanic, Muratore; Bernardeschi, Higuain, Ronaldo
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