Lorenzo Insigne is expected to start for Napoli with Dries Mertens and Jose Callejon, but there are mixed reports on what tactics and formation Barcelona will use.
The Champions League Round of 16 tie kicks off tonight at Camp Nou, at 20.00 UK time (19.00 GMT).
The first leg ended 1-1 at the Stadio San Paolo back in February, so the Partenopei need to win, or draw by scoring at least two goals.
Napoli’s major question mark is over captain Insigne, who limped off with a groin injury during the final minutes of the 3-1 win over Lazio last week.
He took part in the full training session on Friday and did not feel pain, so if he passes another fitness test this morning, it’s safe to say Insigne will be in the starting XI.
Mertens is expected to start rather than Arkadiusz Milik, who is on the transfer market after refusing to sign a new contract, with Callejon the favourite rather than Matteo Politano to complete an old-school trident.
David Ospina is tipped to start in goal, with Diego Demme rather than Stanislav Lobotka in the middle of the park.
As for Barcelona, there are some different reports on which system coach Quique Setien will employ following a disappointing Liga campaign.
He has very limited choices, because Ousmane Dembele, Samuel Umtiti and Jean-Clair Todibo are injured.
Arthur Melo is refusing to play after signing for Juventus, so is negotiating a contract termination.
Arturo Vidal and Sergio Busquets are suspended, Martin Braithwaite not in the UEFA squad, with Antoine Griezmann, Clement Lenglet and Ronald Araujo recovering from injury setbacks.
There are even reports goalkeeper Marc-Andre Ter Stegen might require knee surgery once the season has concluded.
In Spain, Mundo Deportivo suggest a 4-3-1-2 formation with Lionel Messi supporting Luis Suarez and Griezmann.
They tip Ivan Rakitic, Sergi Roberto and Frenkie de Jong for the midfield trio.
However, La Gazzetta dello Sport propose a revolutionary 3-4-3 approach from Setien, to deal with the shortage of players.
This would have Nelson Semedo, Gerard Pique and Lenglet in the back three, with Jordi Alba and Sergi Roberto as the wing-backs.
Barcelona (4-3-1-2): Ter Stegen; Semedo, Pique, Lenglet, Jordi Alba; Sergi Roberto, Rakitic, De Jong; Messi; Suarez, Griezmann
Napoli (4-3-3): Ospina; Di Lorenzo, Manolas, Koulibaly, Mario Rui; Fabian Ruiz, Demme, Zielinski; Callejon, Mertens, Insigne
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