Federico Chiesa is in the starting line-up, but Fiorentina must cope without Franck Ribery against Sampdoria, who count on Gaston Ramirez.
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There are many transfer targets in action tonight, but Chiesa might be the biggest story of them all.
The Italy international has been strongly linked with Juventus in recent days, as the Viola continue to negotiate with the Old Lady.
This could be his last game for the Viola, as the transfer market closes on Monday, and Gaston Ramirez is in a similar position for the opposition from Genoa.
Sampdoria count on the Uruguayan to help Fabio Quagliarella out on top, as Antonio Candreva continues at right.
Beppe Iachini must cope without French winger Ribery, but has made space for Jack Bonaventura, Sofyan Amrabat, Gaetano Castrovilli and Cristiano Biraghi in a midfield five, with Chiesa at right.
Fiorentina (3-5-2): Dragowski, Milenkovic, Ceccherini, Caceres; Chiesa, Bonaventura, Amrabat, Castrovilli, Biraghi; Kouame, Vlahovic
Sampdoria (4-4-2): Audero; Bereszynski, Yoshida, Tonelli, Augello; Candreva, Thorsby, Ekdal, Damsgaard; Ramirez, Quagliarella