Lazio coach Simone Inzaghi has Ciro Immobile back in the line-up against Borussia Dortmund in the Champions League.
The match kicks off at 20.00 UK time.
The Aquile are expected to come out in a 3-5-2 formation for their comeback in the prestigious competition and Inzaghi looks to side the strongest side possible for his debut in the Champions League.
Strakosha will be in goal, with Patric, Luiz Felipe and Francesco Acerbi completing the defensive line.
Lazio coach Simone Inzaghi has Ciro Immobile back in the line-up against Borussia Dortmund in the Champions League.
The match kicks off at 20.00 UK time.
The Aquile are expected to come out in a 3-5-2 formation for their comeback in the prestigious competition and Inzaghi looks to side the strongest side possible for his debut in the Champions League.
Strakosha will be in goal, with Patric, Luiz Felipe and Francesco Acerbi completing the defensive line.
Adam Marusic and Mohamed Fares are expected to start out wide, with Sergej Milinkovic-Savic and Luis Alberto given the go ahead in the middle of the park, on either side of Brazilian Lucas Leiva.
Up front, Italy international Immobile is back in action and could pair up with Joaquin Correa.
But the visitors come with some of the most talented attackers in the competition, as Erling Braut Haaland and Jadon Sancho are expected to start for Die Schwarzgelben.
Dortmund coach Lucien Favre will have captain Marco Reus in behind the two strikers, offering valuable experience in the support role.
BVB seem set to start in a usual 3-4-1-2 formation, with Lukasz Piszczek, Mats Hummels and Thomas Delaney at the back.
Thomas Meunier and Raphael Guerreiro could start out wide, with Jude Bellingham and Axel Witsel in the centre.
Lazio (probable): Strakosha; Patric, Luiz Felipe, Acerbi; Marusic, Milinkovic-Savic, Leiva, Luis Alberto, Fares; Immobile, Correa
Dortmund (probable): Burki; Piszczek, Hummels, Delaney; Meunier, Bellingham, Witsel, Guerreiro; Reus; Sancho, Haaland
Referee: Turpin (FRA)