The Insigne brothers face off in the Campania Derby, as Pippo Inzaghi’s Benevento take on unpredictable Gennaro Gattuso’s Napoli.
It kicks off at 14.00 GMT, you can follow all the build-up and action as it happens from today’s five Serie A games on the LIVEBLOG.
This is only Benevento’s second ever Serie A season, so it’s a rare fixture that has hardly ever been played and a huge occasion for the local team.
Le Streghe have already shown they are not afraid to shake up the bigger clubs, having beaten Sampdoria and Bologna, while losing 5-2 to both Inter and Roma.
Nicolas Viola, Gabriele Moncini and Federico Barba are still out of action, but Roberto Insigne is picked to complete the trident with Gianluca Lapadula and Gianluca Caprari.
His older brother, Lorenzo, starts for Napoli with Hirving Lozano and Dries Mertens supporting Victor Osimhen.
The Partenopei are remarkably unpredictable, lurching from a 4-1 win over Atalanta to a shock 1-0 Europa League home defeat to AZ Alkmaar on Thursday evening.
Piotr Zielinski and Eljif Elmas finally tested negative for COVID-19 yesterday, but have not been rushed back into the squad.
Benevento: Montipò; Letizia, Glik, Caldirola, Foulon; Ionita, Schiattarella, Dabo; R Insigne, Caprari, Lapadula
Napoli: Meret; Di Lorenzo, Manolas, Koulibaly, Mario Rui; Bakayoko, Fabian Ruiz; Lozano, Mertens, L Insigne; Osimhen