Milan are expected to continue with Zlatan Ibrahimovic in attack and Gigio Donnarumma in goal against LOSC Lille in the Europa League.
The match kicks off at 20.00 UK time.
The Rossoneri have started the European season well with six points from two games and another win against the Ligue 1 side will bring them one step further to confirming a place in the last 32.
After successes against Celtic and Sparta Prague, coach Stefano Pioli seems happy to continue with Donnarumma in goal, behind Manchester United loanee Diogo Dalot, Simon Kjaer, Alessio Romagnoli and Theo Hernandez.
Sandro Tonali returns to the line-up with Franck Kessie in the midfield, as Samu Castillejo has recovered to play at right in a trident with Brahim Diaz and Rade Krunic.
Ibrahimovic continues up front, looking for his first goal in the group stage of the Europa League.
Lille have started the season with 19 points from nine Ligue 1 games and have picked up four points from their two first games in the Europa League.
But they arrive at San Siro on a run of three draws and Christophe Galtier’s men are expected to side a traditional 4-4-2 formation with Renato Sanches in the middle of the park and Turkish striker Burak Yilmaz leading the line.
Milan (probable): Donnarumma; Dalot, Kjaer, Romagnoli, Theo Hernandez; Kessie, Tonali; Castillejo, Brahim Diaz, Krunic; Ibrahimovic
Lille (probable): Maignan; Celik, Fonte, Botman, Reinildo; Yazici, André, Renato Sanches, Bamba; Ikone, Yilmaz
Referee: Frankowski (POL)