Domenico Berardi should replace Federico Bernardeschi against Bosnia, as Italy make one change in the line-up from the win against Poland.
The match kicks off at 19.45 UK time.
After the 2-0 win at the Mapei Stadium secured a place at the top in the UEFA Nations League A Group 1, Alberico Evani is set to lead the men for the third time in Sarajevo.
Italy CT Roberto Mancini is still isolated after testing positive for coronavirus and the Azzurri seem set to count on the same players who secured an impressive win on Sunday.
However, Napoli full-back Giovanni Di Lorenzo fights to replace Alessandro Bastoni in the heart of the defence, but the Inter defender is currently tipped to start again.
But the reports in Italy suggests Sassuolo attacker Berardi will get the go ahead from the first minute in Sarajevo and is expected to replace Juventus winger Bernardeschi.
Lorenzo Insigne and Andrea Belotti will therefore continue in attack, with Jorginho, Nicolò Barella and Manuel Locatelli in the midfield trident.
Bosnia are struggling with absentees due to COVID-19, with Edin Dzeko back in Rome, but former Juventus midfielder Miralem Pjanic should be ready to go.
Milan man Rade Krunic seems set to start in the midfield trident too, as Bosnia are expected to come out in a 4-3-3 formation.
Bosnia (probable): Brasnic; Todorovic, Kovacevic, Sanicanin, Kolasinac; Cimirot, Pjanic, Krunic; Visca, Prevljak, Gojak
Italy (probable): G. Donnarumma; Florenzi, Acerbi, Bastoni, Emerson; Barella, Jorginho, Locatelli; Berardi, Belotti, Insigne
Referee: Soares Dias (POR)