Inter were absolutely clinical at the Mapei Stadium, harassing Sassuolo into errors and making the most of them to end the Neroverdi’s unbeaten record.
This win allowed Antonio Conte’s men to catch Sassuolo in second place on 18 points and inflict the first defeat of the season on Roberto De Zerbi and co.
It was a lightning start with Lautaro Martinez and Alexis Sanchez pouncing on a poor clearance and beating the on-rushing goalkeeper within four minutes.
Arturo Vidal’s cross was then accidentally bundled into his own net by unlucky Vlad Chiriches, who would later go off injured.
Filip Djuricic saw his effort hit the upright for the hosts, but Roberto Gagliardini completed the rout with a sensational half-volley off the outside of the boot.