Stefano Sensi and Borja Valero picked up injuries during the warm-up of Fiorentina-Inter and were replaced with Giacomo Bonaventura and Arturo Vidal.
Inter and Fiorentina meet at the Artemio Franchi in the last 16 stage of the Coppa Italia. It kicks-off at 14.00 GMT.
The Italian midfielder was announced in the Inter starting XI, but picked up an injury during the warm-up was replaced with Arturo Vidal.
The same is true of former Inter midfielder Borja Valero who was expected to start for Fiorentina, but was forced to forfeit and was replaced with Giacomo Bonaventura.