Napoli director Cristiano Giuntoli admits they are in a crisis situation against Atalanta after losing Lorenzo Insigne too.
It kicks off at 17.00 GMT, click here for the line-ups and LIVEBLOG.
There was already a huge injury list beforehand, then Insigne pulled out at the last minute.
“Insigne has back pain, it can happen after so many games and journeys,” Giuntoli told Sky Sport Italia.
It’s a dire situation, especially as they played on Thursday night against Granada in the Europa League.
“We go into this match with great determination and hunger, we know that we’ve got 13-14 lads of real quality and must give our all to emerge from this difficult moment as soon as possible.”
Due to the lack of alternatives, Victor Osimhen is continuing to start, although he still seems very rusty.
“Osimhen was out for a long time, so it’s not easy for him to find his fitness levels quickly. We’ve got him now, he has to keep going and hopefully will find his form.”