Juventus have a massive injury crisis on their hands, forcing Alex Sandro into a back three with Dejan Kulusevski partnering Cristiano Ronaldo in Verona.
It kicks off at the Stadio Bentegodi at 19.45 GMT.
Andrea Pirlo has precious few options to choose from at the moment, as Leonardo Bonucci, Giorgio Chiellini, Juan Cuadrado, Arthur and Paulo Dybala are injured.
Alvaro Morata has not trained all week due to a viral infection, plus Danilo is suspended.
The Bianconeri therefore return to a 3-5-2 formation with Alex Sandro improvising as a centre-back, Federico Chiesa and Federico Bernardeschi taking the wings.
Kulusevski is the only real remaining option to partner Ronaldo, but Weston McKennie is rested in favour of Aaron Ramsey behind the strikers.
Hellas Verona’s own crisis is beginning to ease, with only Nikola Kalinic, Ebrima Colley and Kevin Ruegg still out of action.
However, it was announced this morning that Verona’s matchday squad had a COVID case, although the second bout of tests all came back negative.
The positive player was not named, but is believed to be Marco Benassi.
Kevin Lasagna is hoping to make up for some shocking misses in his first few Verona outings, supported by Mattia Zaccagni and Antonin Barak.
Federico Dimarco returns from suspension and Stefano Sturaro is a surprise pick against his old club.
This is a tricky fixture for Juventus, who have lost two of their last three visits to the Bentegodi.
Verona: Silvestri; Magnani, Gunter, Lovato; Faraoni, Sturaro, Ilic, Dimarco; Barak, Zaccagni; Lasagna
Verona bench: Berardi, Pandur, Veloso, Lazovic, Salcedo, Favilli, Udogie, Ceccherini, Vieira, Dawidowicz, Bessa, Tameze
Juventus: Szczesny; Demiral, De Ligt, Alex Sandro; Chiesa, Bentancur, Rabiot, Bernardeschi; Ramsey; Kulusevski, Ronaldo
Juventus bench: Pinsoglio, Buffon, McKennie, Di Pardo, Dragusin, Frabotta, Fagioli, Raafia, Peeters, Capellini, Marques, Ake