Theo Hernandez and Ante Rebic have been left out of the Milan squad list to face Manchester United tomorrow.
The Rossoneri are facing an injury crisis with Zlatan Ibrahimovic, Mario Mandzukic, Ismael Bennacer and Hakan Calhanoglu who are also out of action.
Theo and Rebic were expected to recover in time for the Old Trafford clash as Stefano Pioli revealed last week they had only picked up knocks in their last home game against Udinese.
However, they are both unavailable against the Red Devils tomorrow.
Pioli can only rely on two strikers against Manchester United: Rafael Leao Riccardo Tonin, a player from their Primavera team.