Henrikh Mkhitaryan is in the Roma squad to face Ajax tomorrow, but Leonardo Spinazzola and Stephan El Shaarawy are still out.
The first leg of the Europa League quarter-final ended 2-1 for the Giallorossi in Amsterdam.
The decider is on Thursday at the Stadio Olimpico, kicking off at 20.00 UK time (19.00 GMT).
Mkhitaryan made his comeback as a substitute at the weekend in a 1-0 victory over Bologna, but might not be fit enough to start tomorrow.
The options remain limited, as Spinazzola, Marash Kumbulla, El Shaarawy and Nicolò Zaniolo are still out of action.
Edin Dzeko is expected to lead the attack with Leonardo Pellegrini, as the Italian is suspended for Sunday’s Serie A match with Torino.
Roma squad for Ajax: Pau Lopez, Mirante, Fuzato, Karsdorp, Ibanez, Santon, Mancini, Calafiori, Morichelli, Cristante, Pellegrini, Villar, Veretout, Diawara, Ciervo, Darboe, Mkhitaryan, Dzeko, Pedro, Mayoral, Perez