Napoli defender Nikola Maksimovic tested positive for COVID, the Partenopei announced.
The 29-year-old is the only Napoli player to have tested positive after the last round of swab tests.
The former Torino defender is "asymptomatic and will spend his quarantine at home," the club announced on Twitter.
Maksimovic played 27 games across all competitions this season and his contract at the Stadio Maradona expires at the end of the season.
Gennaro Gattuso is now short of options in the defensive department as Kalidou Koulibaly has suffered a muscle problem in the calf and will be out for at least two weeks.
Napoli sit fifth in the Serie A table but are just two points short of Atalanta, Milan and Juventus, who are level on points behind newly crowned Champions Inter.
The Partenopei will face Spezia, Udinese, Fiorentina and Verona in the last four games of the season.