Edinson Cavani, Goran Pandev and Marek Hamsik take on Andrea Pirlo, Sebastian Giovinco and Mirko Vucinic in tonight’s Scudetto showdown.
Only six points separate Serie A leaders Juventus from second-placed Napoli and they go head-to-head at the San Paolo. Kick-off is at 19.45 GMT, click here for a match preview. Keep up to date with the action on our Twitter feed.
The Partenopei have a full squad to choose from and Coach Walter Mazzarri has opted for the old-style ‘Three Tenors’ with Hamsik, Pandev and Cavani, leaving Lorenzo Insigne on the bench.
Christian Maggio does start on the right despite poor form since needing surgery for a fractured bone in his hand.
Cavani is desperate to break his six-game goal drought in all club competition.
Juventus are without Martin Caceres, Paolo De Ceglie, Nicolas Anelka, Nicklas Bendtner and Simone Pepe.
Giorgio Chiellini passed a late fitness test on an ankle problem, so starts in the three-man defence with Leonardo Bonucci and Andrea Barzagli.
Pirlo, Claudio Marchisio and Arturo Vidal pull the midfield strings, while Antonio Conte keeps faith with strike partners Giovinco and Vucinic.
Federico Peluso gets the nod rather than Kwadwo Asamoah on the left wing.
Juventus have not conquered the San Paolo in Serie A since September 30, 2000, when Conte was playing in their midfield.
There are reports the Juventus team bus was pelted with eggs when it arrived at the Stadio San Paolo, while it is suggested a window might also have been broken.
Napoli: De Sanctis; Cannavaro, Campagnaro, Britos; Maggio, Inler, Behrami, Zuniga; Hamsik, Pandev; Cavani
Napoli bench: Rosati, Gamberini, Grava, Rolando, Mesto, Dzemaili, Donadel, Armero, Insigne, El Kaddouri, Calaiò
Juventus: Buffon; Barzagli, Bonucci, Chiellini; Lichtsteiner, Pirlo, Vidal, Marchisio, Peluso; Giovinco, Vucinic
Juventus bench: Storari, Rubinho, Asamoah, Marrone, Isla, Pogba, Padoin, Giaccherini, Quagliarella, Matri
See the latest Serie A predictions and betting tips with Eurotips.co.uk