Fiorentina-Juventus is always a fiery occasion, while today also brings Atalanta-Lazio, Torino-Inter and an Emilia-Romagna Derby.
Click here for individual match previews of every single Serie A Week 8 encounter, plus reports from Roma-Napoli, Cagliari-Catania and Milan-Udinese.
The action begins at 11.30am UK time (10.30 GMT) with Lazio aiming to end their travelling curse against Atalanta.
This afternoon Fiorentina-Juventus is one of Serie A’s most keenly-felt grudge matches, while Gian Piero Gasperini makes his Marassi comeback in Genoa-Chievo.
Sassuolo-Bologna is an Emilia-Romagna Derby, with Livorno-Sampdoria and Verona-Parma relegation dogfights.
This evening Inter visit Torino for their first match under new owner Erick Thohir.
See the latest Serie A predictions and betting tips with Eurotips.co.uk