Something’s got to give, as Roma defend their 100 per cent record against an Udinese side unbeaten in 22 home games.
It kicks off at the Stadio Friuli at 14.00 GMT, click here for a match preview.
Rudi Garcia has had the perfect start to his career with the Giallorossi, winning all eight Serie A matches by conceding one goal and scoring 22.
However, this is a huge test of their capabilities, as Francesco Totti and Gervinho are out injured.
Adem Ljajic, Marco Borriello and Alessandro Florenzi therefore create a brand new trident attack.
It’s also difficult because Udinese are unbeaten at the Stadio Friuli in 22 Serie A games.
Antonio Di Natale starts and Roma are his favourite targets, having put 13 goals past them in 24 encounters.
Maurizio Domizzi is the only notable absentee for Francesco Guidolin’s men.
Watch out for Udinese’s jerseys, as their main sponsor today is a local painter and decorator. Michael Nino won the opportunity as part of a new initiative at the club.
Udinese: Kelava; Heurtaux, Danilo, Naldo; Pereyra, Pinzi, Badu, Lazzari, Gabriel Silva; Muriel; Di Natale
Roma: De Sanctis; Maicon, Benatia, Castan, Balzaretti; Pjanic, De Rossi, Strootman; Florenzi, Borriello, Ljajic
See the latest Serie A predictions and betting tips with Eurotips.co.uk