Napoli try to get back into the Scudetto race against plucky Chievo and leaders Juventus visit a revived Lazio today.
It all begins at 17.00 GMT when Rafa Benitez’s Napoli aim to put their surprise 2-2 draw with Bologna behind them against giant-killers Chievo, potentially with Jorginho’s debut.
Juventus target a 13th consecutive Serie A victory, but must get past a Lazio side completely revitalised under Edy Reja.
It’s also their second visit to the Stadio Olimpico this week, having lost the Coppa Italia quarter-final to Roma on Tuesday.
Tomorrow the early kick-off is an intriguing Verona-Roma with Luca Toni facing his former teammates.
Clarence Seedorf’s Milan travel to Cagliari, while Inter hope to end their crisis against bottom of the table Catania.
Livorno-Sassuolo and Sampdoria-Bologna are relegation tussles, but Parma can send Udinese further down the slippery slope.
Torino hope to continue their remarkable campaign when hosting bad travellers Atalanta.
The evening kick-off sees fourth-placed Fiorentina take on Alberto Gilardino’s Genoa, who are fresh from beating Inter.
See the latest Serie A predictions and betting tips with Eurotips.co.uk