Roma and Inter go head-to-head for the International Champions Cup in Philadelphia this evening, as Davide Astori makes his debut.
It kicks off at 18.00 UK time (17.00 GMT) and they are targeting a place in the Miami Final of this tournament.
Walter Mazzarri stands by his 3-5-2 formation and starts summer signing Dodo, who faces his former teammates for the first time.
Nemanja Vidic also starts at the back, though Andrea Ranocchia is rested.
Roma give ex-Cagliari defender Astori his debut in a Giallorossi jersey, while Alessandro Florenzi becomes a makeshift right-back.
Juan Manuel Iturbe, Mattia Destro and Adem Ljajic form a strong trident attack, as Francesco Totti will come on for the second half.
Inter: Handanovic; Andreolli, Vidic, Juan Jesus; Nagatomo, Jonathan, M'Vila, Kuzmanovic, Dodò; Botta, Icardi
Roma: Skorupski; Florenzi, Astori, Castan, Emanuelson; Pjanic, De Rossi, Nainggolan; Iturbe, Destro, Ljajic
See the latest Serie A predictions and betting tips with Eurotips.co.uk