Serie A leaders Napoli face a tricky trip to Lazio, as they seek a seventh straight win to keep Juventus behind them.
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The Partenopei are on fine form and still two points clear at the top of the table after six consecutive victories, something the club hadn’t achieved for 28 years.
Maurizio Sarri is forced into some changes, as Allan and Elseid Hysaj are suspended with new signing Alberto Grassi injured following a problem in his first training session.
Fellow January buy Vasco Regini is on the bench, as Cristian Maggio and David Lopez step in.
Lazio have been deeply unpredictable all season, but their home form has been particularly shaky.
Before the 4-1 win over 10-man Chievo last weekend, they hadn’t celebrated at the Olimpico since October.
On Sunday the Aquile failed to break down 10-man Udinese in a 0-0 draw, but they are unbeaten in seven rounds, drawing four of them.
Alessandro Matri, Danilo Cataldi and Sergej Milinkovic-Savic are all suspended, with the injury list including Lucas Biglia, Ricardo Kishna, Stefan Radu, Milan Bisevac, Edson Braafheid and Stefan de Vrij.
Federico Marchetti returns in goal after a lengthy lay-off due to a muscle he pulled while celebrating a goal.
Napoli humiliated Lazio 5-0 when they met at the San Paolo in September and have a strong recent record, losing just one of their last seven Serie A encounters, home and away.
The hosts haven’t won this League fixture since a 3-1 result in April 2012, followed by one draw and two victories.
There’s even more reason than usual to fear Gonzalo Higuain. Not only has he scored 22 goals in 22 Serie A rounds – matching the Capocannoniere-winning total from last season already – but Lazio are his favourite victims.
Pipita has put an astonishing 11 goals past Lazio in just 10 encounter in all competition.
In Serie A alone Higuain bagged a hat-trick, three braces and a one-goal outing in just five games.
Lazio: Marchetti; Basta, Mauricio, Hoedt, Konko; Parolo, Onazi, Lulic; Candreva, Klose, Felipe Anderson
Napoli: Reina; Maggio, Albiol, Koulibaly, Strinic; David Lopez, Jorginho, Hamsik; Callejon, Higuain, Insigne