Juventus look to Paulo Dybala and Gigi Buffon’s record in what is sure to be a fiery Derby della Mole against Ciro Immobile’s Torino.
It kicks off at 14.00 GMT, follow the build-up and action from all eight games as it happens on the LIVEBLOG.
The Bianconeri crashed out of the Champions League on Wednesday with a 4-2 extra time defeat at Bayern Munich, having been 2-0 up until the 72nd minute.
Max Allegri has to refocus his players on the Scudetto race with Napoli nipping at their heels, but Giorgio Chiellini, Claudio Marchisio and Martin Caceres are still out of action.
Dybala is available again after missing the Munich trip with a muscular problem and can start with Mario Mandzukic.
This could be an historic occasion, as if Buffon manages not to concede in the opening four minutes, he’ll break Sebastiano Rossi’s all-time Serie A record of 929 minutes, set in 1993-94 at Milan.
Torino have almost the entire squad at their disposal, save for Danilo Avelar, and it’s a very special game for ex-Juve striker Immobile.
Bruno Peres scored a sensational coast-to-coast goal in the derby last year and will take part in a fascinating duel with Stephan Lichtsteiner down that flank.
Toro have lost 12 of their last 14 meetings with Juve, home and away in all competition, save for a 0-0 draw in February 2008 and 2-1 Serie A victory in April 2015.
These sides met twice already this season, Juan Cuadrado snatching a last-gasp winner in the 2-1 Serie A result and a 4-0 hammering in the Coppa Italia.
There is growing tension ahead of the derby, as following a row on Friday, a popular local bar that hosts Torino ultras was set on fire.
Torino: Padelli; Maksimovic, Glik, Moretti; Bruno Peres, Acquah, Gazzi, Benassi, Gabriel Silva; Belotti, Immobile
Torino bench: Ichazo, Castellazzi, Molinaro, Obi, Bovo, Zappacosta, Farnerud, Lopez, Gazzi, Baselli, Martinez, Jansson
Juventus: Buffon; Rugani, Bonucci, Barzagli; Lichtsteiner, Khedira, Lemina, Pogba, Alex Sandro; Dybala, Mandzukic
Juventus bench: Neto, Rubinho, Zaza, Morata, Hernanes, Cuadrado, Padoin, Asamoah, Sturaro, Evra, Pereyra
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