Inter are forced to revamp their defence and start Stevan Jovetic in a tricky trip to relegation battlers Frosinone.
It kicks off at the Matusa at 14.00 UK time (13.00 GMT), click here for a match preview.
The Nerazzurri’s hopes of qualifying for the Champions League suffered a massive blow with last week’s shock 2-1 home defeat to Torino.
Inter are forced to revamp their defence and start Stevan Jovetic in a tricky trip to relegation battlers Frosinone.
It kicks off at the Matusa at 14.00 UK time (13.00 GMT), click here for a match preview.
The Nerazzurri’s hopes of qualifying for the Champions League suffered a massive blow with last week’s shock 2-1 home defeat to Torino.
Roberto Mancini’s men are without an away victory since January 6, scraping just three points from their last six Serie A trips.
Joao Miranda and Yuto Nagatomo are both suspended following their red cards against Torino, so the defence has to be reshuffled.
Inter opt for a 4-4-2 formation with Jovetic given a very rare start supporting centre-forward Mauro Icardi.
Ivan Perisic and Jonathan Biabiany take wide midfield roles, while Felipe Melo is picked ahead of Gary Medel and Geoffrey Kondogbia.
This is a return to the Matusa for Eder, who scored 20 goals in 52 games for Frosinone between 2007 and 2009.
The Italo-Brazilian is yet to find the net in an Inter jersey since arriving from Sampdoria in January.
Frosinone were thrashed 4-0 at Genoa last week, but are a completely different team when playing on home turf.
Hitman Federico Dionisi is suspended and Paolo Sammarco injured, so Oliver Kragl and Luca Paganini support Daniel Ciofani.
Frosinone: Leali; Rosi, Ajeti, Blanchard, Pavlovic; Gucher, Gori, Frara; Paganini, D Ciofani, Kragl
Inter: Handanovic; D'Ambrosio, Murillo, Juan Jesus, Telles; Biabiany, Melo, Brozovic, Perisic; Jovetic, Icardi
Ref: Tagliavento