Napoli can secure automatic Champions League access with a win over Frosinone, but Gonzalo Higuain can also make history.
It kicks off at the Stadio San Paolo at 19.45 UK time (18.45 GMT), follow this game, Milan–Roma and Sassuolo–Inter on the LIVEBLOG.
Maurizio Sarri’s men need a victory to be sure of second place and send Roma into the preliminary round for the Champions League.
Napoli can secure automatic Champions League access with a win over Frosinone, but Gonzalo Higuain can also make history.
It kicks off at the Stadio San Paolo at 19.45 UK time (18.45 GMT), follow this game, Milan-Roma and Sassuolo-Inter on the LIVEBLOG.
Maurizio Sarri’s men need a victory to be sure of second place and send Roma into the preliminary round for the Champions League.
Higuain starts in attack and is only two goals away from matching Gunnar Nordahl’s all-time Serie A record of 35 for a single season, set with Milan in 1949-50.
Pipita has scored an extraordinary 33 goals in just 34 Serie A appearances.
Raul Albiol sits out a ban and is the only absentee, replaced by Vlad Chiriches in the back four.
Frosinone are already relegated, but promised to give their best in this difficult trip as they salute the top flight.
It’s a familiar environment for Coach Roberto Stellone, who wore the Napoli jersey as a striker for four years.
He can’t count on Francesco Bardi, Danilo Soddimo and Luca Paganini to start.
These sides have met only four times before this, Napoli winning four and drawing 1-1 in Serie B back in December 2006.
When they faced off in January, Frosinone were crushed 5-1, including a Higuain brace.
Napoli: Reina; Hysaj, Chiriches, Koulibaly, Ghoulam; Allan, Jorginho, Hamsik; Callejon, Higuain, Insigne
Frosinone: Zappino; M Ciofani, Russo, Blanchard, Crivello; Frara, Gori, Sammarco, Kragl; D Ciofani, Dionisi