Frank de Boer makes his Inter debut this evening against Celtic and is expected to field Mauro Icardi with Ever Banega in a 4-2-3-1 system.
The tactician took over last week after Roberto Mancini surprisingly terminated his contract by mutual consent, just 13 days before the start of the Serie A season.
De Boer was due to make his debut against Borussia Monchengladbach on Wednesday, but the friendly was called off due to a thunderstorm.
He is instead going to open his tenure in Limerick, Ireland, for the International Champions Cup against Scottish club Celtic tonight at 19.00 UK time (18.00 GMT).
Cristian Ansaldi, Marcelo Brozovic and Rodrigo Palacio are injured, but Napoli and Chelsea transfer target Icardi is expected to lead the attack.
De Boer should try out a 4-2-3-1 system with Eder, Banega and Ivan Perisic providing the creativity ahead of solid midfield pairing Gary Medel and Geoffrey Kondogbia.
There is only a week to go before the opening Serie A match against Chievo and Jeison Murillo is suspended for that tie, so Andrea Ranocchia is given a dress rehearsal tonight.
Summer signing Antonio Candreva is in the squad and should make his Inter debut in the second half.
Celtic: Fasan; Ralston, Ambrose, O'Connell, Izaguirre; McGregor, Johansen, Christie, Armstrong; Griffiths, Ciftci
Inter: Handanovic; D'Ambrosio, Ranocchia, Miranda, Nagatomo; Medel, Kondogbia; Eder, Banega, Perisic; Icardi